The Jikei University School of Medicine · Graduate School of Medicine / Faculty of Medicine · 准教授

Research keywordscancer immunology・melanoma therapy・monoclonal antibodies・mesothelioma・cell cycle regulation・unconventional protein secretion

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• Parallel inhibition of platelet-activating factor-induced protein phosphorylation and serotonin release by K-252a, a new inhibitor of protein kinases, in rabbit platelets
• Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription.
• Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling.
• Novel Reporter System Monitoring IL-18 Specific Signaling Can Be Applied to High-Throughput Screening.

• 肝がんにおける型破り分泌の分子機構の解明
• ヒト化抗体とCD26の核内移行によるRNAポリメラーゼII標的抗がん療法の開発
• 早期肝がんに対するPKCδ を⽤いた新規⾼感度診断法の開発
• 核内移行するヒト化抗CD26抗体によるスーパーエンハンサー標的抗がん療法の開発

• Official profile