Juntendo University · Graduate School of Medicine / Faculty of Medicine

Research keywordsNeurology・BPAN・Neurodegenerative disorders・Parkinson’s disease・Rare diseases・医学・歯学・薬学・保健・Autophagy・Neuroscience

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• Pathogenic insights to Parkin-linked model mice.
• Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice.
• Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice.
• Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice.

• パーキンソン病の凝集体形成に着眼した病態解明と新規薬剤の開発
• 興奮性シナプス伝達の破綻を示すBPANノックアウトマウスを用いた病態解明
• ミトコンドリアプロテオスタシスに着眼した凝集体形成機序の解明
• ミトコンドリアプロテオスタシスに着眼した凝集体形成機序の解明

• Official profile