Juntendo University · Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences · 教授

Research keywords薬物送達システム・siRNA送達・リポソーム・高分子ナノ粒子・マイクロスフェア製剤・遺伝子ベクター・ペプチド修飾ナノミセル・網膜薬物送達・難溶性薬物溶解改善・酵母細胞壁賦形剤

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• Effects of surface charge and flexibility of liposomes on dermal drug delivery
• A Multifunctional Hybrid Nanocarrier for Non-Invasive siRNA Delivery to the Retina.
• Intra-articular Retention and Anti-arthritic Effects in Collagen-Induced Arthritis Model Mice by Injectable Small Interfering RNA Containing Hydrogel
• Preparation of spray-dried microparticles using Gelucire 44/14 and porous calcium silicate or spherical microcrystalline cellulose to enhance transport of water-insoluble pranlukast hemihydrate across Caco-2 monolayers

• 血中滞留性を向上した網膜標的光応答型siRNA送達システムの構築
• 後眼部指向型ナノ粒子点眼剤の設計に向けた粒子構造及び眼内移行性解析と至適処方構築
• 血液網膜関門を回避する低侵襲性網膜指向型核酸送達システムの構築

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