Kagoshima University · Graduate School of Medical and Dental Sciences

Research keywords糖尿病・糖尿病性神経障害・糖尿病合併症・神経障害性疼痛・IENFD・血栓形成

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• 堀切 陽祐, 小木曽 和磨, 當房 卓也, 堂薗 直樹, 久保 徹, 楠元 公士, 大保 崇彦, 山神 大, 川出 茂, 倉野 美穂子, 有村 愛子, 橋口 裕, 出口 尚寿, 西尾 善彦2024 · 記述言語： 日本語 出版者・発行元： (一社)日本内分泌学会
• Horinouchi S., Deguchi T., Mukai M., Ijuin A., Kawamoto Y., Nishio Y. . Assessment of the severity of diabetic polyneuropathy aids in predicting the risk of developing diabetic complications i2024 · 記述言語： 日本語 出版者・発行元： Frontiers in Endocrinology This study aimed to determine the efficacy of assessing the severity of diabetic polyneuropathy (DPN) in patients with untreated diabetes. Seventy-two patients with untreated type 2 diabetes who were hospitalized for glycemic control were enrolled and divided into the following two groups: patients who had no prior diagnosis and patients who were unattended or had discontinued treatment. Electrophysiological criteria consistent with Baba’s classification were used to diagnose and assess the severity of DPN. The patients were divided into three subgroups: no DPN (stage 0), mild DPN (stage 1), and moderate or more-severe DPN (stages 2–4). Intergroup comparisons were performed for the clinical characteristics and the results of the nerve conduction studies. Twenty-two (30%), 25 (35%), and 25 (35%) patients were categorized into the no DPN, mild DPN, and moderate or more-severe DPN subgroups, respectively. The number of patients who were unattended or had discontinued treatment in the moderate or more-severe DPN subgroup was significantly higher than that in the no DPN subgroup. The patients in the moderate or more-severe DPN subgroup had an increased risk of developing diabetic retinopathy and nephropathy, with odds ratios of 19.5 and 11.0 for advanced stages of retinopathy and nephropathy, respectively. Thus, the assessment of the severity of DPN could aid in the prediction of the risk of developing diabetic complications in patients with untreated diabetes. DOI： 10.3389/fendo.2024.1380970 Scopus PubMed
• 出口 尚寿 . 特集 プライマリケア医に必要な情報をまるっと整理 くすりの使い方便利帳 第6章 代謝系に作用する薬剤 [糖尿病治療薬] 糖尿病性神経障害治療薬 . 内科131 ( 4 ) 848 - 853 2023年4月 詳細を見る 出版者・発行2023 · 出版者・発行元： 南江堂 DOI： 10.15106/j_naika131_848 CiNii Research
• 郡山 暢之, 鎌田 哲郎, 出口 尚寿, 西尾 善彦2021 · 記述言語： 日本語 出版者・発行元： (一社)日本糖尿病学会

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