Ryugaku Jinja · Professor Archive
Public Professor Archive
Kosuke OKUYA奥谷 公亮
Kagoshima University · Division of Veterinary Medicine, School of Agriculture, Fisheries and Veterinary Medicine · 助教
- Publications
- 4
- Projects
- 4
- Keywords
- 6
留学
神社Kagoshima University · Division of Veterinary Medicine, School of Agriculture, Fisheries and Veterinary Medicine · 助教
Research keywordsveterinary virology・avian influenza・porcine reproductive syndrome virus・wildlife disease surveillance・surrogate animal models・SARS CoV 2 animal studies
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- Okuya K, Oshiro M, Ozawa M . Porcine reproductive and respiratory syndrome associated with a recombinant virus between two commercial modified-live vaccine strains. . Vet2026 · 担当区分: 筆頭著者 記述言語: 英語 DOI: 10.1016/j.vetmic.2026.111007 PubMed
- 「養豚界」2025年9月号2025 · 株式会社 緑書房 2025年9月
- Esaki M, Okuya K, Onuma M, Ozawa M . Genetically distinct H5N2 high pathogenicity avian influenza virus isolated from a peregrine falcon on Amami-Oshima Island, Japan, harboring enhanced patho2025 · 担当区分: 筆頭著者 記述言語: 英語 出版者・発行元: Virology We report the first confirmed case of high pathogenicity avian influenza virus (HPAIV) infection in a peregrine falcon (Falco peregrinus) on Amami-Oshima Island, a region known for its unique biodiversity. The isolate, A/peregrine falcon/Kagoshima/5704A001/2025 (H5N2), showed genetic and phylogenetic divergence across all eight gene segments. Specific amino acids in the PA protein associated with increased pathogenicity in birds and mammals were also identified. Despite global surveillance, related ancestral viruses remain unreported. These findings highlight the need for expanded geographic surveillance and timely, transparent data sharing to better track and respond to emerging HPAIV threats. DOI: 10.1016/j.virol.2026.110794 Scopus PubMed
- Isoda N, Hew LY, Nishikawa K, Takaya F, Shimazu Y, Kobayashi D, Nabeshima K, Honjyo H, Esaki M, Okuya K, Soda K, Ito H, Kumagai A, Nishiura H, Hiono T, Takakuwa H, Usui T, Ozawa M, Uchida Y, Onuma M,2024 · 担当区分: 筆頭著者 記述言語: 英語 出版者・発行元: Pathogens Genetic and antigenic analyses were performed on highly pathogenic avian influenza viruses (HPAIVs) isolated in Hokkaido, northern Japan, during the winter of 2024–2025. Ninety-eight HPAIVs were isolated from feces of waterfowl, tracheal swabs from dead wild birds, or lung homogenates from dead chickens. Phylogenetic analysis of the hemagglutinin (HA) gene from 47 representative isolates revealed that all sequences belonged to the G2d subgroup of clade 2.3.4.4b H5HA, which has been the dominant lineage in Hokkaido since the winter of 2021–2022. These isolates were further divided into three major groups within the subgroup. The HPAIVs isolated in the Republic of Korea, China, and North America were genetically closely related to the Hokkaido isolates, whereas no HPAIVs genetically related to European strains or those detected in North American cattle were identified. Furthermore, HPAIVs isolated from seabirds were genetically closely related to those found in dead marine mammals along the eastern coast of Hokkaido in the spring of 2025. No apparent antigenic differences were observed between the HPAIVs isolated in this study and those from previous seasons. These findings highlight the wide distribution of HPAIVs in Hokkaido, particularly from Asian and North American lineages, and underscore the importance of continuous surveillance. DOI: 10.3390/pathogens14090951 Scopus PubMed
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