Azabu University · Faculty of Environmental Science · 教授

Research keywordsDNA損傷修復・ゲノム不安定性・染色体・研究室: 免疫学研究室

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• MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress.
• Critical role of CRAG, a splicing variant of centaurin-γ3/AGAP3, in ELK1-dependent SRF activation at PML bodies.
• A requirement of FancL and FancD2 monoubiquitination in DNA repair.
• Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.

• ゲノム安定性維持機構の破綻による男性不妊の分子メカニズムの解明
• DNA損傷修復ネットワークの解析
• 染色体安定性と相同DNA組換えに関わる遺伝子群の機能解析
• 脱ユビキチン化による、DNA損傷修復機能制御の解明

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