Azabu University · Faculty of Veterinary Medicine / Graduate School of Veterinary Medicine · 教授

Research keywords分子生物学・エピジェネティクス・DNAメチル化・UHRF1・ICF症候群

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• Cutting-edge insights into DNA methylation maintenance
• Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN
• A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats
• Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway

• ICF症候群とエピゲノム制御の分子基盤
• ゲノムインプリンティングにおいてＵＨＲＦ１が果たす役割の解明
• 癌抑制遺伝子PTENの下流遺伝子の単離と機能解析
• 染色体不安定性を呈する遺伝性疾患の分子病態解明と加齢性疾患への波及的理解

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