Azabu University · Faculty of Life and Environmental Sciences · 教授

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• Long non-coding RNA MANCR is a target of BET bromodomain protein BRD4 and plays a critical role in cellular migration and invasion abilities of prostate cancer
• Nicotine- and tar-free cigarette smoke extract induces cell injury via intracellular Ca2+-dependent subtype-specific protein kinase C activation.
• Glutathione and cysteines suppress cytotoxicity of gas phase of cigarette smoke by direct reacting with unsaturated carbonyl compounds in the gas phase.
• Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation

• Ｇタンパク質共役型受容体結合蛋白質による受容体シグナル制御の多様性と普遍性の解明
• 腫瘍微小環境をリモデリングする遺伝子改変型の新規T細胞製剤の作製
• Rasを介する細胞増殖と分化の調節機構
• SUMO化による網膜幹細胞・未分化前駆細胞の増殖制御機構の解析

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