Kanazawa Medical University · Faculty of Medicine, Immunology

Research keywordsdendritic cell・transcription factor・factor irf8・immunity by lactobacillus pentosus strain・toll-like receptors for dendritic・nk1 1 cell-dependent activation

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• The extract of Japanese soybean, Kurosengoku activates the production of IL-12 and IFN-γ by DC or NK1.1(+) cells in a TLR4- and TLR2-dependent manner.
• [Transcription factors in the development of myeloid cells].
• Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells
• Mutation is the Main Driving Force in the Diversification of the Vibrio splendidus Clade

• 腸管樹状細胞を支配する転写プログラムの解明
• 新規自然リンパ球の同定とその機能解明
• 制御性Ｔ細胞機能を司る転写制御機構の解明

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