Kanazawa University · Cancer Research Institute

Research keywordslipid metabolism・fatty acid metabolism・retinoblastoma protein・endometrial carcinoma・cholesterol synthesis・cancer metabolism・lysophospholipids・triacylglycerols

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat.
• Cytotoxic activity of dimeric acridone alkaloids derived from Citrus plants towards human leukaemia HL-60 cells
• Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
• Control of undifferentiated state by RB tumor suppressor

• RBがん抑制遺伝子の代謝制御機能
• PGAMによるエピジェネティクスリモデリングを介したがん悪性化機構の解明
• Pgamによるグルコース代謝リプログラミングを標的としたがん幹細胞克服法の開発
• 晩期再発乳がんにおける休眠トリガーと分子機構の解明

• Official profile