Kanazawa University · Pharmaceutical Sciences Division · 助教

Research keywords薬物代謝酵素・薬物代謝・薬物トランスポーター・薬物動態

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• Coordinated cytochrome P450 expression in mouse liver and intestine under different dietary conditions during liver regeneration after partial hepatectomy.
• Comparative study of the effect of 17 parabens on PXR-, CAR- and PPARα-mediated transcriptional activation.
• Attenuation of phenobarbital‐induced cytochrome P450 expression in carbon tetrachloride‐induced hepatitis in mice models
• Hydrolytic metabolism of phenyl and benzyl salicylates, fragrances and flavoring agents in foods, by microsomes of rat and human tissues

• ニコチンまたは喫煙による前立腺がんの悪性化におけるRNA修飾異常の関与
• 薬物代謝酵素と薬物トランスポーターの遺伝子発現における相互調節機構の解明
• Functional analysis and visualization of G-quadruplex formation in the dihydrofolate reductase gene for improving chemotherapy
• 薬物動態学的相互作用の病態による変動と予測

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