International University of Health and Welfare · Faculty of Health and Medical Sciences, Narita, Department of Medical Technology · 准教授

Research keywordsliquid biopsy・circulating tumor DNA・lung cancer genomics・KRAS NRAS BRAF mutations・gastric cancer genomic changes・thymoma GTF2I mutation・PALB2 mutations・pan cancer genomics

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• Rapid decrease of circulating tumor DNA predicted the treatment effect of nivolumab in a lung cancer patient within only 5 days.
• Liquid biopsy of wash samples obtained via endoscopic ultrasound-guided fine-needle biopsy: Comparison with liquid biopsy of plasma in pancreatic cancer.
• Molecular subtype switching in early-stage gastric cancers with multiple occurrences.
• Touch imprint cytology with massively parallel sequencing (TIC-seq): a simple and rapid method to snapshot genetic alterations in tumors.

• 細胞診検体由来超微量細胞を用いた全トランスクリプトーム増幅と融合遺伝子検出
• 超微量腫瘍細胞からでも可能な新たながん遺伝子パネル検査法の開発- Whole genome amplification法の細胞診検体への応用-
• 2014年度地方独立行政法人山梨県立中央病院院内学術研究費助成
• がんパネル検査におけるarchived cytology検体の有用性の検討

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