International University of Health and Welfare · Faculty of Pharmaceutical Sciences · 准教授

Research keywordsバイオマーカー・個別化医療・薬物動態・臨床薬理・質量分析・TDM・がん

Research fields医療薬学・Urology・薬理学

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• Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats.
• High-throughput liquid chromatography/electrospray ionization tandem mass spectrometry method using in-source collision-induced dissociation for simultaneous quantification of imatinib, dasatinib, bosutinib, nilotinib, and ibrutinib in human plasma.
• Simultaneous analysis of drugs administered to lung transplanted patients using liquid chromatography tandem mass spectrometry for therapeutic drug monitoring.
• Simultaneous analysis of oral anticancer drugs for renal cell carcinoma in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.

• 免疫チェックポイント阻害薬による自己免疫疾患関連有害事象のバイオマーカー探索
• 薬物動態・薬理遺伝学に基づく腎癌分子標的薬の個別化投与設計法の確立
• 腎癌における免疫チェックポイント阻害薬の個別化投与法の確立

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