International University of Health and Welfare · Faculty of Pharmaceutical Sciences · 講師

Research keywords神経薬理学・行動薬理学・脳腸相関・うつ病・ミエリン

Research fieldsNeuroscience in general・薬系衛生、生物化学・行動薬理学

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• Effect of Globin Digests on Physical Fatigue in Mice.
• Microinjection of brain-derived neurotrophic factor into the dorsal hippocampus alleviates cognitive dysfunction and increases hippocampal cell proliferation in olfactory bulbectomized mice
• Dopamine D2 receptor supersensitivity in the hypothalamus of olfactory bulbectomized mice.
• Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.

• 腸内細菌叢の不均衡によるうつ発症機序の解明：海馬AMPKの関与と新規治療法の開発
• 脳腸相関の概念を基軸としたストレス適応機構の解明と新規うつ病治療法の開発への応用
• 脳内アンジオテンシン変換酵素２の機能解析と新規うつ病治療薬の開発
• 食塩の過剰摂取を伴った認知機能障害の発症機序解明と性差を考慮した創薬展開

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