Kawasaki Medical School · Faculty of Medicine / Graduate School of Medicine · 講師

Research keywords免疫制御・研究・分野

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• LUBAC活性を制御する新規RING型ユビキチンリガーゼの機能解析
• Type I interferon promotes PD-1 transcription and limits the duration of T cell-mediated immunity
• HOIPIN-1, a novel LUBAC inhibitor, suppresses the imiquimod-induced psoriasis-like skin inflammation in mice
• PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells

• 新規オートファジー制御因子Rufy4の機能と免疫応答における意義の解明
• ALSの分子病態解明と治療法開発を目指した直鎖ユビキチンの新規特性解析
• 免疫系特異的オートファジー制御因子Rufy4による炎症応答制御

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