Kawasaki Medical School · Faculty of Medicine / Graduate School of Medicine · 教授

Research keywordsprosaposin biology・saposin D・glycosphingolipids・Krabbe disease・Parkinson disease genetics・glucocerebrosidase activation・phytoceramides・embryonic development

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• Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination2023 · Journal of Neurochemistry
• The Urinary Bladder is Rich in Glycosphingolipids Composed of Phytoceramides2022 · Journal of lipid research
• Variants in saposin D domain of prosaposin gene linked to Parkinson's disease.2020 · Brain

• 膀胱移行上皮細胞の頂端膜機能を担うセラミド骨格の構造多様性2023
• クラッベ病の病態を悪化させるメカニズムの探索2023
• リソソーム病とオートファジーを繋ぐ分子：プロサポシンの機能解析2022
• クラッベ病の新たな病態メカニズム「悪玉マクロファージ仮説」の提唱2022

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