Kawasaki Medical School · Faculty of Medicine / Graduate School of Medicine · 講師

Research keywords(geometry)・Amyloid・Arc・Biophysics・Cell・Cycloheximide・Hippocampal・Histone

Research fieldsMolecular biology・Pathological medical chemistry・Neuroscience in general・Cell biology

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• ARC/ARG3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles
• Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter.
• Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo
• A nanobody-based proximity ligation assay detects constitutive and stimulus-regulated native Arc/Arg3.1 oligomers in hippocampal neuronal dendrites

• 神経セロイドリポフスチン症の視力障害はプロサポシンの発現亢進で説明でき るか？
• 網膜色素変性症の新たな病態仮説：Prosaposinopathy（プロサポシノパチー）の提唱
• 中枢神経グリア細胞間の情報伝達メカニズムの研究
• Pax3遺伝子へのレトロトランスポゾンの挿入が神経管閉鎖不全を引き起こすメカニズムの解明

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