Keio University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences

Research keywordsplacental transporters・fetal drug transfer・metformin transport・olmesartan transport・OATP2B1・OAT4・BCRP・syncytiotrophoblasts

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• Rat-Specific Expression of Placental MATE1 Contributes to Species Difference in Fetal Transfer of Metformin and 1-Methyl-4-Phenylpyridinium2025 · Molecular Pharmaceutics 22
• Fetal ezrin expression affects macrophages and regulatory T cells in mouse placental decidua2024 · Biochemical and Biophysical Research Communications 735 2024年11月
• Involvement of GAT2/Slc6a13 in hypotaurine uptake at fetal-facing plasma membrane of syncytiotrophoblasts at mid-to-late gestation in rats and mice2024 · Placenta 147
• Conversion of Olmesartan to Olmesartan Medoxomil, A Prodrug that Improves Intestinal Absorption, Confers Substrate Recognition by OATP2B12024 · Pharmaceutical Research 41

• Ex vivo-in silicoハイブリッドによるヒト胎児薬物移行の新解析プラットフォーム構築2024 · -
• 胎盤内分泌破綻の早期予測に向けた胎盤関門因子の同調制御解析2023 · -
• 有機酸取り込みトランスポーターを標的とした腎不全予防法の提案2022 · -
• 尿細管の両面動態にアプローチする先天性代謝疾患治療法の開拓2020 · -

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