Keio University · Faculty of Medicine / Graduate School of Medicine · 助教

Research keywordsAquaporin・Circadian・Cooling・Created・Expressing Rat・Humanized・Light・Neuromyelitis

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• Cooling-rate dependence of the cryopreservation of aquaporin-overexpressing cells with a non-permeable cryoprotectant2025 · Cryobiology 119 2025年06月
• Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainage pathways2024 · Scientific Reports 14
• Humanized-Aquaporin-4-Expressing Rat Created by Gene-Editing Technology and Its Use to Clarify the Pathology of Neuromyelitis Optica Spectrum Disorder2024 · International Journal of Molecular Sciences 25
• A tyrosine-based YXXΦ motif regulates the degradation of aquaporin-4 via both lysosomal and proteasomal pathways and is functionally inhibited by a 10-amino-acid sequence within its C-terminus2023 · FEBS Journal

• アクアポリン４機能と脳リンパ排泄機構に着目したアルツハイマー病発症機構の解明2017 · -
• 視神経脊髄炎の動物モデルと抗アクアポリン４抗体を用いた新規治療法の開発基盤研究2016 · -
• アルツハイマー病モデルマウスを用いたAβ蓄積から神経原繊維変化へ至る機構の解明2013 · -
• アクアポリン4ノックアウトマウスを用いた新規視神経脊髄炎モデルの作製とその解析2010 · -

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