Kindai University · Faculty of Medicine

Research keywords肺癌・分子科学・Uniportal VATS・区域肺切除・ロボット支援下胸腔鏡手術・EGFR変異・ctDNA

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• How to demarcate intersegmental plane with resected-segments inflation method using the slip knot technique in thoracoscopic anatomic segmentectomy.
• The preoperative assessment of subpleural lung cancer movement to distinguish thoracic wall adhesion or invasion using four-dimensional computed-tomography.
• Thoracoscopic anatomical lung segmentectomy using 3D computed tomography simulation without tumour markings for non-palpable and non-visualized small lung nodules.
• Secondary mutations of the EGFR gene that confer resistance to mobocertinib in EGFR exon 20 insertion.

• 切除可能な臨床病期II-III期非小細胞肺癌に対する術前療法後手術と手術先行療法に関するランダム化比較第III相試験（JCOG2317）
• EGFR/HER2 exon 20 挿入変異モデルに対する新規 TKI の獲得耐性機序の解明
• 臨床病期IA3期の肺野末梢充実型非小細胞肺癌に対する肺葉切除と区域切除のランダム化比較試験（WJOG16923L：STEP UP）
• 網羅的生体情報を活用した肺がんゲノム治療の確立

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