Kindai University · Faculty of Medicine · 講師

Research keywordsCADM1・mast cell biology・cell adhesion molecules・antibody-drug conjugates・gastrointestinal stromal tumors・endometrioid carcinoma・cell survival signaling

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• Expression of a soluble isoform of cell adhesion molecule 1 in the brain and its involvement in directional neurite outgrowth.
• Urinary Cell Adhesion Molecule 1 Is a Novel Biomarker That Links Tubulointerstitial Damage to Glomerular Filtration Rates in Chronic Kidney Disease.
• Increased ectodomain shedding of cell adhesion molecule 1 as a cause of type II alveolar epithelial cell apoptosis in patients with idiopathic interstitial pneumonia.
• Elevated Hydrostatic Pressure Causes Retinal Degeneration Through Upregulating Lipocalin-2.

• 末梢神経に高親和性の抗体による疼痛・掻痒の抑制
• 接着分子を標的とする肺気腫治療の創薬シーズ探索
• 接着分子CADM1が基軸となる慢性腎臓病の尿細管間質病変形成
• 肺気腫の新規発症機序：接着分子CADM1の細胞内断片による肺胞上皮アポトーシス

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