Kindai University · Faculty of Medicine · 教授

Research keywordsDNA損傷応答・腫瘍生物学・エピゲノム・加齢・細胞死・代謝制御・ヒストン脱メチル化酵素

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• Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model
• Modulation of transient type K channel cloned from rat heart.
• Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure
• KDM4B promotes acute myeloid leukemia associated with AML1-ETO by regulating chromatin accessibility.

• エピジェネティクスによる老化制御機構の解明
• To investigate the roles of histone demethylases in estrogen receptor signaling Network
• Establishment of in vivo and in vitro models for systematic tissue-specific epigenomic mapping
• 核酸医薬による変異K-RAS遺伝子発現制御と革新的抗癌薬の開発

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