Kindai University · Faculty of Pharmaceutical Sciences · 教授

Research keywordsリボソーム・統合的ストレス応答・遺伝子発現転写後制御・酸化ストレス・SMG1・がん抗原・ナンセンス依存性mRNA分解・mRNA翻訳・mRNA監視機構・mRNA分解

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• Angiotensin II Type 1 Receptor-Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin.
• Simultaneous measurement of nascent transcriptome and translatome using 4-thiouridine metabolic RNA labeling and translating ribosome affinity purification.
• Versatile applications of transcriptional pulsing to study mRNA turnover in mammalian cells
• Structures of SMG1-UPFs Complexes: SMG1 Contributes to Regulate UPF2-Dependent Activation of UPF1 in NMD

• RNA監視機構による遺伝子発現制御
• 小分子ＲＮＡ作用マシナリーの調節機構
• mRNA監視機構に起因する神経疾患の病態と治療に関する研究
• 老化関連脳心血管病における受容体結合因子の病態生理学的意義

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