Kindai University · Faculty of Agriculture · 教授

Research keywordsEpigenetics・DNA Methylation・X-inactivation・X染色体不活性化・エピジェネティクス・クロマチン・ノンコーディングRNA・DNAメチル化・Xist・SmcHD1

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• The mouse Gtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA
• Mosaic methylation of Xist gene before chromosome inactivation in undifferentiated female mouse embryonic stem and embryonic germ cells
• Effect of Tsix disruption on Xist expression in male ES cells
• Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain

• 長鎖ノンコーディングRNAのクロマチンターゲティング
• Molecular Mechanisms of X-inactivation
• ヘテロクロマチン形成とクロマチン環境
• X染色体不活性化センターにおけるアンチセンス制御機構

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