The University of Kitakyushu · Graduate School of Environmental Engineering / Faculty of Environmental Engineering · 教授

Research keywordsTRPC6-associated FSGS・cell cortical stiffness・ERM dephosphorylation・actin cytoskeleton mechanics・SARS-CoV-2 spike-ACE2 interaction・alpha-mangostin・vascular smooth muscle differentiation・3D collagen mineralization・cell biomechanics

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• Delayed inactivation of TRPC6 as a determinative characteristic of FSGS-associated variants2025 · Journal of Biological Chemistry
• Interaction of SARS-CoV-2 Spike protein with ACE2 induces cortical actin modulation, including dephosphorylation of ERM proteins and reduction of cortical stiffness2025 · Human Cell
• Mutations in the SARS-CoV-2 Spike proteins affected the ACE2-binding affinity during the development of Omicron pandemic variants2024 · Biochem Biophys Res Commun
• Alpha-mangostin dephosphorylates ERM to induce adhesion and decrease surface stiffness in KG-1 cells2022 · Human Cell

• エクソソームによる骨組織形成制御と骨組織によるエクソソーム貯蔵2024 · 科学研究費助成事業
• ヒト筋線維芽細胞の平滑筋細胞形質転換にかかる分子機構の解析と形質転換要素の同定2021 · 科学研究費助成事業 基盤研究(C)
• エクソソームを基軸とした石灰化形成機構の解明2016 · 科学研究費補助金 基盤研究(C)
• 石灰化に対する各種細胞外基質分子の効果2015 · リバネス研究費 富士フイルム賞

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