Kitasato University · Graduate School of Pharmaceutical Sciences / Department of Pharmacy / Faculty of Pharmaceutical Sciences · 教授

Research keywordscholesterol ester metabolism・ACAT inhibition・atherosclerosis・macrophage lipid metabolism・ER stress・autophagy induction

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• Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp.
• Design, Synthesis, and Biological Evaluation of Beauveriolide Analogues Bearing Photoreactive Amino Acids.
• Binding of phenochalasin A, an inhibitor of lipid droplet formation in mouse macrophages, on G-actin
• Total syntheses of mavintramycin A and its structural analog, cytosaminomycin C, and evaluation of their antibacterial activities against Mycobacterium avium and Mycobacterium intracellulare

• トリプルネガティブ乳がん共通のバイオロジーを標的とした新規医薬品の探索
• 日本学術振興会 海外特別研究員
• 多様性に富んだインドネシアの生物資源の収集と有効活用
• 中性脂質蓄積制御からの脂肪肝/脂肪肝炎の予防治療薬の開拓

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