Kitasato University · Graduate School of Pharmaceutical Sciences / Department of Pharmacy / Faculty of Pharmaceutical Sciences · 助教

Research keywords医学・歯学・薬学・保健

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• Reverse Fosmidomycin Analogs as Bisubstrate Inhibitors: Binding Mode Elucidation and Mechanistic Insights2026
• The Diverse Binding Modes Explain the Nanomolar Levels of Inhibitory Activities Against 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase from Plasmodium falciparum Exhibited by Reverse Hydroxamate Analogs of Fosmidomycin with Varying N-Substituents2025
• The stability of NPM1 oligomers regulated by acidic disordered regions controls the quality of liquid droplets2023
• The Stat3 inhibitor F0648-0027 is a potential therapeutic against rheumatoid arthritis2022

• 隠れた薬物結合ポケットを標的とした創薬を志向した知識ベース計算手法の開発2023
• タンパク質表面の隠れたドラッガブルポケットを同定するための新規計算機手法の開発2020
• 低分子量のPPI阻害剤開発のためのインシリコ・フラグメントマッピング法の確立2018

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