Kobe University · University Hospital · 助教

Research keywordsantimicrobial stewardship・infectious disease consultation・Gram stain diagnostics・HIV care・COVID-19 immunology・antibiotic duration optimization・drug-drug interaction management・bacteremia treatment・acute cholangitis

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• Tixagevimab and cilgavimab投与後に汎血球減少によりCOVID-19肺炎が再燃した一例2024 · 日本感染症学会・日本化学療法学会, 2024年05月, 日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集, 98回・72回, np279 - np279, 日本語
• Accuracy of classification of urinary Gram-stain findings by a computer-aided diagnosis app compared with microbiology specialists.2022 · Introduction. Timely and accurate diagnosis of bacterial infections enables early administration of appropriate antimicrobial treatment and improved outcomes.Hypothesis/Gap Statement. The accuracy of computer-aided diagnosis (CAD) for identifying organisms on urine Gram stains has not been compared with that of microbiology specialists (MS).Aim. To compare the interpretation of urine Gram-stain results by MS and a CAD app designed using artificial intelligence.Methodology. Urine specimens from patients with urinary tract infections were used and collected at two tertiary hospitals between 1 April and 31 December 2022. Using non-inferiority analysis to assess whether CAD was non-inferior to expert interpretation, CAD-predicted microscopic findings of the Gram-stained slide generated from iPhone camera images from two hospitals were compared with those from ten MS. A total of 153 images were taken from each hospital, and CAD interpreted a total of 306. The primary endpoint was the prediction accuracy based on the morphology of the Gram-stained bacteria.Results. The accuracy (95% confidence interval) of MS and CAD predictions was 83.0% (81.6%-84.3%) and 87.9% (83.7%-91.3%), respectively, with a difference of -4.93% (-8.43% to -0.62%) indicating non-inferiority of CAD.Conclusion. CAD was non-inferior to MS predictions for identifying Gram-stained pathogens; therefore, CAD was suggested to have the potential for guiding empirical antibiotic selection in patients with urinary tract infections.
• 造血幹細胞移植後患者における組換え型帯状疱疹ワクチンの安全性についての検討2022 · 日本感染症学会西日本地方会・日本感染症学会中日本地方会・日本化学療法学会西日本支部, 2022年09月, 日本感染症学会西日本地方会学術集会・日本感染症学会中日本地方会学術集会・日本化学療法学会西日本支部総会プログラム・抄録集, 92回・65回・70回, 269 - 269, 日本語
• 大動脈十二指腸瘻に対する腹部大動脈人工血管置換術後4ヵ月後に発症したM.intracellulareによる播種性感染2022 · (一社)日本感染症学会, 2022年03月, 感染症学雑誌, 96(臨増) (臨増), 148 - 148, 日本語

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