Kobe University · Graduate School of Medicine / Faculty of Medicine · 講師

Research keywordscongenital cytomegalovirus・maternal cmv screening・igg avidity・hhv-6 reactivation・stem cell transplantation・gynecologic oncology

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• Low Geriatric-8 Score as a Potential Risk Factor for Minimally Invasive Surgery in Elderly Patients With Gynecologic Malignancies.2019 · BACKGROUND: The Geriatric-8 (G8) is a validated screening tool for identifying frailty in elderly cancer patients. Although minimally invasive surgery (MIS) is increasingly performed in older adults with gynecologic malignancies, few studies have evaluated the association between G8 scores and perioperative complications in this setting. METHODS: This single-center retrospective study included patients aged ≥ 65 years who underwent MIS for gynecologic malignancies between January 2019 and March 2024. G8 scores were retrospectively calculated using medical records, with a threshold of ≤ 12.5 indicating geriatric risk. Perioperative complications were defined as either (1) Clavien-Dindo classification or CTCAE version 5 grade II or higher within 30 days postoperatively or (2) the need for rehabilitation intervention due to a decline in activities of daily living (ADL). Univariate and multivariate logistic regression analyses were conducted to identify associated factors. RESULTS: A total of 68 patients were included (median age: 72.5 years). The median G8 score was significantly lower in the complication group than in the non-complication group (12.5 vs. 14.5, p = 0.008). In multivariate analysis, a G8 score ≤ 12.5 was independently associated with perioperative complications (OR: 4.02, 95% CI: 1.38-11.70, p = 0.011). No significant associations were found for operative time, hysterectomy, or lymphadenectomy. CONCLUSION: A low G8 score was independently associated with perioperative complications and may be useful for preoperative risk assessment in elderly patients undergoing MIS for gynecologic malignancies.
• トラベクテジンにより長期間病勢コントロールを行った平滑筋肉腫の1例2018 · 「産婦人科の進歩」編集室, 2018年05月, 産婦人科の進歩, 70(2) (2), 234 - 234, 日本語
• Human CD134 (OX40) expressed on T cells plays a key role for human herpesvirus 6B replication after allogeneic hematopoietic stem cell transplantation.2018 · 2018年05月, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 102, 50 - 55
• Expression of CD134 (OX40) on T cells is a trigger of human herpesvirus 6B reactivation and replication after hematopoietic cell transplantation.2018 · 2018年05月, J Clin Virol., 102, 50 - 55

• 生殖不全とhuman herpesvirus 6 & 7との関係解明 長又 哲史 科学研究費補助金／若手研究, 2018年04月 - 2021年03月, 研究代表者 競争的資金2018 · KUID parsed section
• 生殖不全とhuman herpesvirus 6 & 7との関係解明
• miR-622内包人工エクソソームによる卵巣癌の浸潤・転移と微小環境制御

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