Kochi University · Graduate School of Integrated Human and Natural Sciences · 教授

Research keywordsアレルギー・皮膚癌・皮膚・活性酸素・乾癬・フリーラジカル・アトピー性皮膚炎・角化症

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• COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.
• A comparative split-face study of two types of application methods with clindamycin phosphate lotion 0.1% in patients with acne vulgaris
• PD-L1 positive macrophages were increased in a case of pembrolizumab-induced bullous pemphigoid.
• Inhibition of nuclear factor kappa B activation and inducible nitric oxide synthase transcription by prolonged exposure to high glucose in the human keratinocyte cell line HaCaT

• 表皮角化細胞の増殖と血管内皮細胞増殖因子産生に及ぼす各種活性酸素の影響
• 皮膚バリア機構破綻アトピー性皮膚炎モデルマウスの酸化ストレス状態と治療
• ロリクリン角皮症の病態解明(RNA干渉法を用いて)
• アトピー性皮膚炎における自然免疫低下のメカニズムの解明と治療

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