Kyoto Prefectural University of Medicine · Graduate School of Medicine

Research keywordsゲノム編集・細胞分化・転写因子・がん代謝・遺伝子発現

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• Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded vMIP-I and vMIP-II induce signal transduction and chemotaxis in monocytic cells
• Venetoclax efficacy on acute myeloid leukemia is enhanced by the combination with butyrate
• The combination of venetoclax and quercetin exerts a cytotoxic effect on acute myeloid leukemia
• Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1

• RUNX1による造血幹細胞分化プロセスの解明と新たな分子標的薬の開発
• 造血関連転写因子RUNX1遺伝子の発現制御機構の解明と新規治療法開発への応用
• 白血病関連転写因子RUNX1の発現機構の解析と造血系予防医学への応用
• アミノ酸シグナルを担うトランスポーター依存的mTOR活性化機構の解明

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