Kyoto Prefectural University of Medicine · Graduate School of Medicine · 准教授

Research keywords腫瘍微小環境・薬剤抵抗性・がん幹細胞・分子標的治療

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• PRRX1 upregulates PD-L1 in human mesenchymal stem cells
• Runx2 function in cells of neural crest origin during intramembranous ossification.
• Establishment of a tTA-dependent photoactivatable Cre recombinase knock-in mouse model for optogenetic genome engineering.
• The Novel Monoclonal Antibody 9F5 Reveals Expression of a Fragment of GPNMB/Osteoactivin Processed by Furin-like Protease(s) in a Subpopulation of Microglia in Neonatal Rat Brain

• 肉腫細胞特異的インタラクトームを標的とした新規治療薬の開発
• 間葉系幹細胞による免疫抑制効果のメカニズム解明
• 増悪因子間の相互作用を標的とした新規肉腫治療薬コンセプトの検証
• セマフォリンシグナルの阻害が導くがん治療の新たな展望

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