Sojo University · Faculty of Pharmaceutical Sciences · 准教授

Research keywordswith・核膜孔, がん, ヌクレオポリン, DNA複製・phospholipids・Acidic・unsaturated・fatty

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• Kinetics of ATP binding to the origin recognition complex of Saccharomyces cerevisiae.
• The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype.
• Sequence-independent DNA binding activity of DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli.
• ADP-binding to origin recognition complex of Saccharomyces cerevisiae.

• 核膜孔因子Nup88によるソニックヘッジホッグ経路を介したがん悪性化の分子基盤
• 細胞選択的ネクローシス誘導による治療抵抗性がん治療の高度化
• Ｎｕｐ８８の分子間相互作用解析によるがん発症・転移促進機構の解明
• 真核生物の染色体DNA複製の試験管内再構成と、複製開始制御機構の解明

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