Sojo University · Faculty of Pharmaceutical Sciences · 教授

Research keywords抗体 Fab・医学・歯学・薬学・保健

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• A novel engineered interchain disulfide bond in the constant region enhances the thermostability of adalimumab Fab.
• Domain separation and characterization of PriC, a replication restart primosome factor in Escherichia coli.
• Inhibitory effects of SSRIs on IFN-γ induced microglial activation through the regulation of intracellular calcium.
• Crystal structures of K33 mutant hen lysozymes with enhanced activities.

• ハブ毒腺組織特異的な転写調節分子機構の解明
• NMRを用いた難治性疾患ALアミロイドーシスの発症機構の解明と阻害法の確立
• 超耐熱化蛋白質融合抗体フラグメントの創製
• 抗体フラグメントFabの高度な安定化と医薬への応用

• Official profile