Sojo University · Faculty of Biology and Life Sciences · 准教授

Research keywords統合失調症・アミノ酸・スフィンゴ脂質・神経変性疾患・精神疾患

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• Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects.
• Lipid Pathology of the Corpus Callosum in Schizophrenia and the Potential Role of Abnormal Gene Regulatory Networks with Reduced Microglial Marker Expression.
• ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment.
• Adaptive response to l-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts.

• 精神疾患様行動異常へのスフィンゴ脂質シグナル経路の関与の解明
• 神経毒性スフィンゴ脂質による精神疾患発症のメカニズム解明
• スフィンゴ脂質代謝変化を伴う精神疾患病態メカニズムの分子基盤の解明
• ヒト死後脳を用いた統合失調症の病態メカニズムとスフィンゴ脂質の関連の解明

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