Kumamoto University · Faculty of Pharmaceutical Sciences / Graduate School of Biomedical Sciences (Pharmaceutical Sciences Division) / Graduate School of Pharmaceutical Education

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• Improving purity and apparent thermal stability of single-chain Fv antibodies by heat treatment in a soluble E. coli cytoplasmic expression system.2026 · Journal of biochemistry
• Structure-based design and biophysical characterization of the linker sequence that associate to the VH-VL domain interface of the single-chain Fv antibody to suppress oligomerization propensity.2026 · Protein science : a publication of the Protein Society
• Structure-based design, biophysical characterization, and biochemical application of the heterodimeric affinity purification tag based on the Schistosoma japonicum glutathione-S-transferase (SjGST) homodimer2024 · The Journal of Biochemistry
• Contribution of Phe112, Ser114, and Tyr115 to Drug-Binding Selectivity in the A Variant of α1-Acid Glycoprotein2024 · Molecular Pharmaceutics

• 構造生物学・物理化学・計算化学に基づくチロシンキナーゼ阻害剤剤選択性の解明2024 · 科学研究費助成事業
• 多彩な構造を有する天然物の迅速評価による核内受容体の活性化・阻害と構造の相関解析2022 · 科学研究費助成事業
• 抗がん剤耐性克服へ向けた核内受容体の活性制御機構の解明2021 · 科学研究費助成事業 基盤研究(C)
• TTR単量体の変性、凝集体形成の分子機構の解明と遺伝性難病FAPの創薬への応用2018 · 科学研究費助成事業 基盤研究(C)

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