Kumamoto University · Institute of Molecular Embryology and Genetics · 教授

Research keywordspiRNA biogenesis・germ plasm assembly・hemimethylated DNA recognition・chromatin remodeling・meiotic entry・pluripotency transitions・spermatogenesis・embryonic stem cells

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• Abundant piRNA production mediated by the Drosophila GTSF1 homolog Tpp ensures Aubergine localization and germ plasm assembly.2025 · Proceedings of the National Academy of Sciences of the United States of America
• The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS.2024 · Nucleic acids research
• STRA8–RB interaction is required for timely entry of meiosis in mouse female germ cells2023 · Nature Communications
• The role of Zfp352 in the regulation of transient expression of 2‐cell specific genes in mouse embryonic stem cells2023 · Genes to Cells

• クロマチン複製における転写因子ネットワークの継承機構の解析2019 · 科学研究費助成事業
• マウスES細胞において開いたクロマチンの状態を規定する分子機構の解明2017 · 科学研究費助成事業
• 多能性幹細胞と栄養外胚葉幹細胞の運命を分ける転写因子とエピジェネティクスの階層性2013
• 多能性幹細胞のシステムズバイオロジー:転写因子ネットワークのメタ解析とシミュレーションによるロバストネスを持つ不均一性の理解2010

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