Kumamoto University · Faculty of Medicine, Department of Medicine / Graduate School of Life Sciences (Medical Sciences) / Graduate School of Medical Education · 准教授

Research keywordsANGPTL2・tumor microenvironment・immune checkpoint therapy・bone metastasis・muscle atrophy・lysosome

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• Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy.2024 · Cancer gene therapy
• Host ANGPTL2 establishes an immunosuppressive tumor microenvironment and resistance to immune checkpoint therapy.2024 · Cancer science
• Loss of Dja2 accompanies pH deviation in lysosomes and lysosome-related organelles.2023 · Journal of cellular physiology
• ANGPTL2 promotes immune checkpoint inhibitor-related murine autoimmune myocarditis.2023 · Communications biology

• DjA2 KOマウスの示す酸性オルガネラ内腔pH調節異常の分子基盤の解明2008 · 科学研究費助成事業
• 異常タンパク質応答の生理的役割の解明2007 · 科学研究費助成事業
• 一酸化窒素(NO)合成とNO依存性アポトーシスの制御2002 · 科学研究費助成事業
• 動物における分子シャペロンの機能解析2002 · 科学研究費助成事業

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