Kurume University · Research Institute of Molecular Life Science · 講師

Research keywordsメタボライト・DNA切断酵素・ゲノム安定性・CRISPR-Cas9・CRISPRi・Genetics Gene Restriction・Genome Molecular・Biochemistry

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• Proliferation Analyses of Conditional Knockdown Strains Using CRISPR Interference in Fission Yeast2024 · Methods in Molecular Biology, 2024年11月12日,
• Genetic knockdown of genes that are obscure, conserved and essential using CRISPR interference methods in the fission yeast S. pombe2023 · Journal of Cell Science, 2023年05月,
• Transcriptional Regulation Technology for Gene Perturbation in Fission Yeast2023 · Biomolecules, 2023年04月21日,
• Implementation of dCas9-mediated CRISPRi in the fission yeast Schizosaccharomyces pombe2021 · G3: Genes | Genomes | Genetics, 2021年02月,

• 革新的な転写抑制医薬品の開発～dCas9タンパク質の人工進化～
• 分裂酵母のCRISPRiを用いた産業価値の高い代謝物質の生産
• 分裂酵母を用いた高価代謝物質の生産
• 分裂酵母の必須遺伝子ノックダウンライブラリ構築とその応用

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