Kobe Women's University · Faculty of Health and Welfare, Department of Health, Sports and Nutrition · 教授

Research keywords生物無機化学・分析化学・食品化学・糖尿病・亜鉛錯体・インスリン様作用

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• 卵巣摘出マウスにおける細胞死および細胞老化関連蛋白の発現に関する検討
• Insulinomimetic Zn(II) complexes as evaluated by both glucose-uptake activity and inhibition of free fatty acids release in isolated rat adipocytes
• A family of insulinomimetic zinc(II) complexes of amino ligands with Zn(Nn) (n=3 and 4) coordination modes
• Oral Administration of Bis(aspirinato)zinc(II) Complex Ameliorates Hyperglycemia and Metabolic Syndrome-Like Disorders in Spontaneously Diabetic KK-A(y) Mice: Structure-Activity Relationship on Zinc-Salicylate Complexes

• タンパク質のO-グリコシル化亢進にもとづく２型糖尿病発症機構の解明と改善薬の開発
• 糖尿病治療効果を有する金属錯体の開発
• 敗血症予防効果を有する免疫機能強化性亜鉛錯体の開発研究
• α－グルコシダーゼ阻害効果をもつ金属錯体の開発研究

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