Kyoto University · Center for iPS Cell Research and Application · 准教授

Research keywordsneural stem cells・choroid plexus・cerebrospinal fluid・Wnt signaling・mTOR signaling・circuit plasticity

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• The choroid plexus- cerebrospinal fluid axis as a lifespan regulator of neural stem cells and circuit plasticity.2026
• The influence of the choroid plexus on brain function: beyond its role in cerebrospinal fluid production.2025
• E3 ubiquitin ligase RMND5A maintains the self-renewal state of human neural stem/precursor cells by regulating Wnt and mTOR signaling pathways.2025
• Multifaceted Regulation of Neural Stem Cell Fate in the Developing Brain2024

• 脈絡叢分泌性miRNAを標的とした新規抗老化治療戦略の開拓2024
• 神経発生、発達における細胞外小胞を介したトランスエピジェネティクス制御機構の解明2024
• 脈絡叢変容による脳内液性環境老化の分子機構2022
• 神経幹細胞のニューロン産生能低下に呼応したDNAメチル化獲得領域の意義2020

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