Kyoto University · Center for iPS Cell Research and Application

Research keywordsNF-kB signaling・B-cell responses・exhausted CD8 T cells・regulatory T cells・thymic epithelial development・Bach2 transcription factor・Th2 immunity・hematologic malignancy

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• CIN85 regulates the canonical NF-κB pathway and subsequent B cell responses.,2011 · J. Exp. Med., 208(7):1447-57, 2011,
• Altered immune function and hematologic malignancy in SPA-1-deficient mice2004 · IMMUNOLOGY 2004: AUTOIMMUNITY, GENETIC AND DEGENERATIVE DISORDERS, MALIGNANCIES, AND TRANSPLANTATION,
• Identification of a T-bethi Quiescent Exhausted CD8 T Cell Subpopulation That Can Differentiate into TIM3+CX3CR1+ Effectors and Memory-like Cells.1950 · Journal of immunology (Baltimore, Md. : 1950),
• Bone Marrow Endothelial Cells Take Up Blood-Borne Immune Complexes via Fcγ Receptor IIb2 in an Erythropoietin-Dependent Manner.1950 · Journal of immunology (Baltimore, Md. : 1950),

• Ｂリンパ球自己免疫寛容獲得、維持機構の解明―ＣＩＮ８５によるＢＣＲ制御の観点より
• ヒトMHC拘束性機能的ヒトT細胞の解析を可能にする免疫ヒト化マウスの作出

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