Kyoto University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences · 准教授

Research keywordstrophoblast biology・3D cell culture・nerve growth factor・BMP-2 signaling・TNF signaling・TGF-beta signaling・fibroblast growth regulation

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• Spheroid formation induces chemokine production in trophoblast-derived Swan71 cells.1989 · American journal of reproductive immunology (New York, N.Y. : 1989),
• Biochemical characterization of placental leucine aminopeptidase/oxytocinase and its related enzyme, adipocyte-derived leucine aminopeptidaseCELL-SURFACE AMINOPEPTIDASES: BASIC AND CLINICAL ASPECTS,
• Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cellsEUROPEAN JOURNAL OF BIOCHEMISTRY,
• Involvement of the V-2 receptor in vasopressin-stimulated translocation of placental leucine aminopeptidase/oxytocinase in renal cellsEUROPEAN JOURNAL OF BIOCHEMISTRY,

• 胚シグナルに対する免疫応答異常を共通の病因とする新しい疾患群の同定と解析
• 活性動態の理解に基づいた脱ユビキチン化酵素の機能解明
• 生殖過程における組織再構築機構の解析ー体循環細胞による再生機序の解明を目指してー
• M1アミノペプチダーゼ機能異常と自己免疫疾患病態の分子機構

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