Kyoto University · Faculty of Medicine / Graduate School of Medicine · 特定准教授

Research keywordscryo em・molecular simulation・protein conformational dynamics・free energy landscape・kinase inhibitors・structural biology・drug discovery

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• Generating Free-energy Landscapes and Mapping Conformational Transition Pathways from cryo-EM Images using a Deep Isometric Autoencoder2025 · 2025年03月05日
• cryoMDM; Molecular simulation Driven structural Matching Approach to Estimate Variety of Atomic Three-dimensional Model Based on Noisy cryoEM Single Particle Images.2024 · 2024年11月01日
• Small-molecule RAS/RAF Binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against a Broad Spectrum of RAS-driven Cancers2024 · 2024年01月23日
• kMoL: an open-source machine and federated learning library for drug discoveryJournal of Cheminformatics,

• 分子構造を基盤としたエボラウイルス治療薬の開発研究
• cryoEM-NMR融合構造解析の確立
• フィロウイルスの増殖機構の分子構造基盤の解明と制御法の開発
• 低分子量G蛋白質Rasの翻訳後脂質修飾の役割の構造科学的研究

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