Kyoto University · Faculty of Medicine / Graduate School of Medicine

Research keywordsフェロトーシス・細胞死・セレン

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• Differential Involvement of the Npl4 Zinc Finger Domains of SHARPIN and HOIL-1L in Linear Ubiquitin Chain Assembly Complex-Mediated Cell Death ProtectionMOLECULAR AND CELLULAR BIOLOGY,
• The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.Nature cell biology,
• Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complexPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
• Light responsive hydrogen selenide (H2Se)/hydrogen diselenide (H2Se2) donors: applied for protein S-selenylation on PRDX6.Chemical science,

• 細胞の生存と死を決定する制御システムの数理モデル化
• 直鎖状ポリユビキチン鎖による細胞死抑制メカニズムの解析
• フェロトーシスを制御する新たな鉄・セレン軸の解明
• 直鎖状ポリユビキチン鎖による細胞生死の運命決定機構の解明

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