Kyoto University · Center for iPS Cell Research and Application

Research keywordsinduced pluripotent stem cells・integration-free reprogramming・totipotency・pluripotency・multi-omics・corneal epithelium・epithelial-mesenchymal transition・early reprogramming

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• Evaluating totipotency using criteria of increasing stringency.Nature cell biology,
• An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells.Stem cells (Dayton, Ohio),
• ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency.PloS one,
• Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells.iScience,

• 網羅的プロテオーム解析によるヒトの細胞種特異的リボソームタンパクの同定と機能解析
• 新規因子によるプラスミドを用いたヒト血球細胞からの人工多能性幹細胞誘導効率の上昇

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