Kyoto University · Graduate School of Life Sciences

Research keywordsgut microbiota metabolites・short-chain fatty acids・GPR41 signaling・GPR119 activation・obesity metabolism・prebiotic exopolysaccharides・peptide YY secretion・feeding behavior

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• Fructooligosaccharides Intake during Pregnancy Improves Metabolic Phenotype of Offspring in High Fat Diet-Induced Obese Mice.Molecular nutrition & food research,
• Medium-chain fatty acid receptor GPR84 deficiency leads to metabolic homeostasis dysfunction in mice fed high-fat diet.FASEB bioAdvances,
• Gut microbial short-chain fatty acids-mediated olfactory receptor 78 stimulation promotes anorexigenic gut hormone peptide YY secretion in mice.Biochemical and biophysical research communications,
• Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides.Nature communications,

• 腸内細菌および短鎖脂肪酸受容体による新規神経機能制御機構の解明
• ケトン体受容体を介した食・栄養環境認識 機構の解明
• 中鎖脂肪酸が腸管発達と疾患リスクに与える影響の解明
• 短鎖脂肪酸受容体Olfr78を介した神経機能制御機構の解明

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