Kyoto University · Faculty of Agriculture / Graduate School of Agriculture · 教授

Research keywords生物有機化学・呼吸鎖・光親和性標識・ユビキノン・ケミカルバイオロジー・Biological organic chemistry・複合体-I・有機合成

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• Amilorides Bind to the Quinone Binding Pocket of Bovine Mitochondrial Complex IBIOCHEMISTRY,
• Dynamic binding of acetogenin-type inhibitors to mitochondrial complex I revealed by photoaffinity labelingBiochimica et Biophysica Acta (BBA) - Bioenergetics,
• Identification of proteins involved in intracellular ubiquinone trafficking in Saccharomyces cerevisiae using artificial ubiquinone probeBiochimica et Biophysica Acta (BBA) - Bioenergetics,
• Mode of inhibitory action of Delta lac-acetogenins, a new class of inhibitors of bovine heart mitochondrial complex IBIOCHEMISTRY,

• ミトコンドリア呼吸鎖複合体-I 阻害剤としての中分子リグナン類の作用機構研究
• Synthesis of functional ubiquione probes and analysis of ubiquinone-binding ptotein
• ユビキノンの新しい生理機能の発掘を目指した細胞内動態の解明
• 呼吸鎖酵素複合体ーＩの鍵サブユニットＮＤ１の機能解明

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