Kyoto University · Center for iPS Cell Research and Application

Research keywords生物学・基礎生命科学・時間・オミクス解析・オルガノイド・幹細胞・遺伝子改変マウス

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• Hypoblast from human pluripotent stem cells regulates epiblast development.Nature,
• Identification and characterization of secreted factors that are upregulated during somatic cell reprogrammingFEBS Letters,
• Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cellsCell Reports,
• Transient expression of WNT2 promotes somatic cell reprogramming by inducing β-catenin nuclear accumulationStem Cell Reports,

• 網羅的解析を用いた神経幹細胞からアストロサイトへの運命決定機構の解明
• 腸内分泌細胞構成の加齢変化とその制御機構の解明
• iPS細胞とリプログラミング技術を用いた臓器老化・若返り研究の基盤構築
• 腸上皮組織の加齢変化が個体老化へおよぼす影響の解明

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