Kyoto University · Graduate School of Life Sciences · 准教授

Research keywordsactin cytoskeleton・tropomodulin・tropomyosin・single molecule microscopy・focal adhesions・actin polymerization・cell motility・IQGAP

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• Essential role of ADF/cofilin for assembly of contractile actin networks in the C-elegans somatic gonadJOURNAL OF CELL SCIENCE,
• Mechanostress resistance involving formin homology proteins: G- and F-actin homeostasis-driven filament nucleation and helical polymerization-mediated actin polymer stabilization.Biochemical and biophysical research communications,
• Mammalian Tropomodulins Nucleate Actin Polymerization via Their Actin Monomer Binding and Filament Pointed End-capping ActivitiesJOURNAL OF BIOLOGICAL CHEMISTRY,
• Force transmission by retrograde actin flow-induced dynamic molecular stretching of TalinNature Communications,

• 高解像度分子可視化による力学的情報メモリの定量的解析
• 蛍光単分子イメージングによる微小環境感知メカニズムの可視化解明
• 革新的蛍光単分子イメージングによるECM-細胞力学的相互作用の解明
• 高精度単分子可視化による細胞−微小環境の力学的情報伝達機構の解明

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